Sandrine was born on February 25, 1968 in Boulogne-Billancourt, France. She married Vincent Lindon in 1989 and they had a child. She was selected as a jury member at the Cannes Film Festival in 2001. She won the César Award for Most Promising Actress for the film En avoir in 1995. Her films include Girls Only (2003), Les Gamins (2013), Life of Riley (2014), In Safe Hands (2018), and Black Tide (2018).