A group of teenagers runs away from their homes after they find out that their parents are undercover super villains, and start to learn about their true selves and about life.
As the Runaways continue to evade their parents and learn to control their powers, Jonah reveals his plans to the Pride as his past is revealed.
After the Runaways split up, and many friends mysteriously disappear, the team has to regroup, and its members are reunited to face Jonah and his family.