In an effort to find Dean, whose whereabouts are unknown, Sam seeks everyone's help. Jack is working out how to live as a human, picking up new talents, and fitting into this hunting community.
Sam discovers a hint regarding Dean's location, so he decides to launch an investigation with Mary and Bobby. Jack receives a few wise words from Castiel as he continues to look for a family link in his frantic need for belonging.
Sam, who is still attempting to figure out what happened to Dean, asks Sheriff Jody Mills for assistance. Mills may already be working on the case without realizing it. Jack continues to look up to Castiel as a father figure.
Sam is forced to think while Dean continues to struggle and finds himself trapped within a real-life horror movie as action figurines come to life.
Sam, Dean, Mary, and Bobby rush to locate Maggie after a hunt goes awry and leaves them uncertain of her location. However, what they discover are their own darkest fears.
Sam and Charlie work together to solve a series of unexplained disappearances. Jack thinks he has a case and persuades Dean to join him on the search.
Sam and Castiel set out on a new search to find a friend who is in urgent need of assistance. While seeking explanations for his wife's passing, Nick keeps going down an unsettling path. A new mystery connects Jack and Dean.
Sam and Dean work together with an unlikely friend. Castiel is forced to make a significant sacrifice in order to set things right as Heaven is under attack by an evil power.
To find out what Michael could be up to, Sam and Dean recruit the help of their friend Garth. The brothers parted ways to seek out weaponry that would help them in their conflict with the Archangel, but it may be a battle that our heroes are unable to succeed in.
As his army of monsters advances, Michael seizes control of Dean once more. Sam comes up with a strategy to go to Dean and defeat Michael before anyone else dies.
Mary, Donna, and Dean enjoy some quality time together. After much investigation, Nick discovers the solution. Sam is forced to make an impossible decision.
When Donatello accidentally disrupts the order of future prophets due to his current state, Sam and Dean must figure out how to put an end to the slaughter. Nick is confronted with his history.
Instead of finding a solution to their most recent issue, Sam and Dean discover far more than any of them had imagined when they turn to supernatural books.
Rowena joins Sam and Dean in their search for a demi-god who eats human flesh. Michael's fate becomes uncertain when he finds himself caught up in an unexpected chase with the past.
Sam and Castiel track a mysterious case in small-town Arkansas. Sam discovers that the city is not as perfect as it seems and that darkness dwells in its corners. To see an old friend, Dean and Jack go on a trip.
While Jack tries to win over a new group of friends, Sam and Dean are perplexed when they encounter a creature they have never heard of before.
Sam and Dean rush to help a friend who is in distress. Castiel asks Jo/Anael for assistance in finding a miracle as Mary worries about Jack's welfare.
Sam and Dean continue their journey in search of a way to help Jack. Jack's condition becomes uneasy as his spirit is completely out of control, and his friends try to help him.
Sam and Dean go off in separate directions to investigate the city's mysterious crimes, but they soon realize that these crimes are connected to them and that they must act to put a stop to the horrific events.
Sam and Dean engage in an epic confrontation with God as the gates of Hell open and life on Earth approaches annihilation. Jack is furious with all the lies around him, but an old friend of his shows up to change everything.