A look at the daily chaos of a Chicago emergency room where the doctors deal with unique new cases and navigate fiery situations in their line of work.
Dr. Charles deals with the fallout of his actions with Sarah's father. Will and Natalie start a new chapter of their lives together. Sharon struggles to come up with a working relationship with the new COO of the hospital. Ethan and April clash over the former's sister.
Will and Natalie fight for their lives after a bad car accident. The death of Cornelius Rhodes is ruled a homicide and an investigation is launched. Dr. Choi races to save a young patient.
In the sixth season, the staff at Gaffney Chicago Medical Center deals with the aftermath of the global pandemic, while saving patients’ lives and grappling with their own personal problems.
In season 9, Dr. Mitch Ripley, an Attending Emergency Physician who is an old acquaintance of Dr. Charles, joins the crew as the team works to help save lives at the hospital in every way possible.