Watson seeks help from a former patient to find a maniacal bomber.
When a local street gang leader kidnaps Holmes to force him to find the person responsible for injuring his men, Holmes and Watson become caught in the middle of an international manhunt to recover a rare artifact.
Holmes discovers a secret about Captain Gregson's girlfriend that could change everything.
Gregson pushes for Holmes and Watson to be placed on local murder lists.
As Shinwell's criminal record prevents him from finding a full-time job, Holmes disagrees with Watson's plan to help him.
Holmes and Watson investigate a mass murder when a cook and his patrons are poisoned with snake venom.
Joan takes drastic measures to ensure that Shinwell will not be drawn back into a life of crime.
Joan becomes concerned that Sherlock is in danger when she learns that he has been lying to her about attending recovery sessions.
Holmes and Watson have three days to catch the real killer before Shinwell is sent back to prison.
Watson becomes embroiled in a Drug Enforcement Agency investigation into doctors who write illegal prescriptions.
Holmes and Watson race to find a woman who has been held captive for years, before the kidnapper takes drastic steps to avoid capture.
When Holmes and Watson investigate the murder of a clown in the Northern State, they discover a link between his death and the creation of a new virus.
Watson is held captive and threatened at gunpoint, and Sherlock is forced to investigate an old case.
Shinwell asks Joan for advice when his daughter asks to see him for the first time in five years.
Holmes's former protege, Kitty Winter, returns to New York after a three-year absence to warn him that a killer is wiping out everyone involved in a case they've worked on.
Joan and Kitty try to prove that a series of murders, stemming from an old case solved by Sherlock and Kitty in London, are linked to an international government conspiracy with the CIA.
The police contact Holmes for help with a mysterious murder, and suspicion returns to Holmes and Watson on Shinwell.
Sherlock and Joan investigate a case involving a legendary pirate and his legendary treasure.
Holmes and Watson investigate the murder of a man Sherlock considers one of New York's worst private detectives.
Holmes and Watson investigate the murder of a magician performing classical tricks, and Watson believes that Bell is being targeted by his ex-girlfriend.
Watson and Holmes search for the suspect believed to be behind Chantal's assault and the suicide of her ex-husband.
After a reality show contestant is murdered, another competitor becomes the prime suspect.
A murder investigation puts Holmes and Watson in the crosshairs of one of New York City's most notorious gangs.
Holmes and Watson pursue a perplexing criminal as a gang war erupts in New York City.