In a post-apocalyptic future, an uneasy treaty allows humans and vampires to live together in the US, albeit on opposite coasts. As both sides plot to destroy the other, the treaty is breached and all hell breaks loose.
Sephora attempts to eradicate vampires through an experiment that, if successful, will change the course of the war, as the remaining humans need to continue fighting to protect themselves and the world from the vampire threat.