As Drew, a therapist who has been recently divorced, discovers he needs a kidney transplant, he gets a surprise offer from an unexpected friend from his past.
In order to secure Gina's proposal, Drew makes her an offer in return.
Gina introduces herself as Drew's kidney donor to his ex-wife when the latter drops in.
With Drew embittered by his divorce, Gina tries to improve his mood, causing a good turn of events.
Tensions arise when Gina finds out that Drew is tracking her movements.
After the pre-kidney donation psychological evaluation is scheduled for Gina, she flips out when she finds out that her ex-boyfriend is getting engaged, causing Drew to panic.
Drew fights with Gina in response to two pieces of bad news and starts to wonder about the worth of his sacrifices.
As Drew notices that his friends drifted away after his divorce, Gina decides to help him by inviting his dialysis group to a party she hosts.
As the dialysis group gets excited when they learn that Jerry found his kidney match, Drew starts making plans that has been postponed for long to carry out with his daughter.
Gina and Drew's friends try to help Drew out following his depression after Jerry's surgery fails.
For the sake of having no issues in the kidney transplant process, Gina takes Drew and Norma to Philadelphia to get her father's medical records.
As Cannoli's owner is returning and Drew is being pushed away by his daughter, Drew and Gina switch roles.
As Norma goes to live with Gina and Drew after she sets her room on fire by accident, feelings surfaces between Gina and Eli.
Gina panics when Eli invites her to attend a family wedding in Las Vegas with him.
While Gina helps Eli get ready for a local sportscaster job audition, Drew meets Adriana and both agree to go on a date.
As Gina helps Norma reconcile with her daughter, she and Drew face obstacles in their new relationships.
Gina and Drew start making future plans when they receive great news from Drew's doctor.
As the surgery day is near, Drew receives a gift from his dialysis group, while Gina plans her future with Eli.