The rebellious doctors and nurses of San Antonio Memorial run the ER night shift using their military background and instincts.
TC is faced with the challenge of performing a heart transplant on a dying deputy sheriff. Meanwhile, Landry's child abuse investigation takes a shocking turn.
TC needs to reattach a hunter's hand, Jordan tries to mediate between family members in order to perform a blood transfusion, while Drew has a hard time keeping an injury hidden.
A reenactment of the battle of the Alamo results in many injuries that challenge the staff. Meanwhile, an amnesiac patient is given care and Drew comes to the aid of an injured soldier.
Topher's pregnant wife is stranded on a highway with her daughter while in labor during a storm. Meanwhile, TC challenges Jordan's boyfriend as he is considered for the position of trauma department head at the hospital.
A military bus accident leaves Drew at risk as his relationship with Rick could be exposed. Meanwhile, TC and Scott fight over Jordan.
The only survivor of a plane crash is treated by TC and Topher, who try to send a prying police officer with ulterior motives away. Meanwhile, Paul treats a severely injured exotic dancer.
Topher's critical condition reminds TC of his brother who died in Afghanistan. Meanwhile, the hospital may face legal problems because of Jordan's treatment of Dwayne's murderer.