It follows the mishaps of Edina Monsoon and her best friend Patsy, who indulge in a reckless life full of drugs, alcohol and cigarettes.
Eddy returns to her former glory while continuing to fight against society's unfair ideas with the support of her friend Patsy, but the death of a family member makes her think about death and the essence of life.
Eddy and Patsy continue their life of booze, illegal drugs, and unwise decisions, as Eddy decides to travel to New York to collect the perfect tools to renovate her home.
As Eddy's interests change, she decides to work in television production instead of public relations, and Patsy is promoted to become managing editor of Chic magazine.
The comedic atmosphere returns in the fifth part, as Eddy becomes a public relations expert for several celebrities and Patsy works with her as her fashion consultant, which allows them to make friends with many in the artistic field.
The adventures of Eddy and Patsy return after twenty years, appearing older but without wisdom. However, the two friends continue to get into many difficult and funny situations and problems.