Sayed Nefisa's seven children gather in the apartment where he has been in a coma for six years. After a life of poverty and miserliness, the children learn that their father has a huge fortune, and at Bossi's suggestion, they devise a plot to murder their father to get the money.
The seven children get bewildered and they bring another corpse from the morgue. When their foul act is discovered, they flee in terror, except for Bossi who gets arrested. At prison, she sees her father in a dream informing her about the seven commandments kept in his old box.
The other six siblings part ways; Hend has to conform to the unfair conditions of those who forged her a new ID, Marmar begs in Alexandria, Sabry is lured by a procurer, Mahmoud partakes in a strange bargain, and Em Em commits another crime, while Monsef is asked to murder a woman.
Bossi is sentenced to seven years in prison, Sabry marries the procurer. Mahmoud succumbs to the wishes of the wife of the carpenter's workshop owner. Hend strikes a bargain that guarantees her survival, and Em Em takes revenge on the landlady for treating her inhumanely.
Bossi's time at prison is getting more intolerable as she has to deal with Nazira and her homosexual tendencies. Likewise, the six siblings try to adapt to their new lives as they try to make money along the way.
At prison, Bossi receives sweeping popularity as stories of her having magical powers spread. Mahmoud learns that he is sterile. Hend learns that her formula has a killer effect. Em Em has to face a witch practicing black magic. Sabry intends to ruin the vicious business of his wife.
When Sabry reports a night girl that works for his wife, the girl reports Sabry's wife. Marmar receives threatening messages divulging the truth about her father's death. Mahmoud is shocked to confirm he's sterile. Monsef strikes a deal with Magda.
When Ossa completes her sentence, Bossi allows her to stay at her house. Em Em and Arnous learn they can't have children. Marmar tries to seize Umm Ahmed's (Ahmed's mother) money after her death.
Bossi considers escaping from prison to read her father's commandments. Monsef is accused of having a hand in Magda's kidnapping. When Umm Ahmed's body is found in the closet, Em Em has to reveal who the murderer is to save Arnous. Mahmoud's son is put for adoption. Mohsen, Hend's husband, is hospitalized.
Upon learning of the plot he has devised against her, Marmar buries her husband alive. Em Em manages to acquit her husband. Monsef collaborates with El-Doksh to get Magda's money. Bossi escapes from prison.
Bossi and Ossa try to find any trace of Bossi's siblings. Hend vows revenge on Mohsen's second wife who knows her secret. Marmar is haunted by her deceased husband's ghost. Sabry tries to expand his prostitution business. Monsef stirs discord between Magda and El-Doksh.
With the help of a lady at the neighborhood, the shrine Bossi made for her father gains increasing popularity. Dalal plots with Mahmoud to get rid of her husband. Monsef confesses his feelings for Magda. Sabry carries on with his plot and marries a procurer at Suez, leaving Esaad in prison.
Bossi learns the whereabouts of her brother Sabry. Esaad learns of Sabry's intention to keep her imprisoned. Ossa and Hend quarrel when Hend returns home to find it turned into a shrine. Monsef is informed of El-Doksh's kidnapping, and Magda refuses to pay the ransom.
Bossi goes with Alia to Suez to meet Sabry and give him his commandment. Sabry is shocked to learn of Esaad's release. Mahmoud is kidnapped. Hend has Ossa kidnapped. Marmar is in trouble when Umm Ahmed's son returns. Shehata reveals Monsef and Magda's plot.
Upon learning the truth, Hend and Ossa travel to Bossi. Nabil, Umm Ahmed's other son, develops a crush on Marmar who cleans the house for him. El-Doksh returns the money that Hamedto paid. Sabry sees Bossi read the commandment concerning him.
Shehata falsely claims she's pregnant, which drives Magda crazy. Em Em learns that Arnous has resorted to magic and witchcraft to have children. Hend refuses to follow what's written in the commandment. Mohsen gets back on his feet and severely beats Hend that she loses her baby.
Hoping to protect herself, Marmar sleeps with Nabil. Mahmoud fears for Dalal's baby. Hend is reluctant about aborting the baby, fearing he might be born with a deformity. Bossi tries to change Sabry's mind.
Dalal attempts to find a way to protect herself, even by wedding the man who caused her abortion. Sabry's wives devise a plan to get Esaad to abort. Karim learns where Bossi is, and he intends to see her to read the commandment.
Karim tries to come to an agreement with Bossi and Ossa. Hend reads the commandment and decides to keep the baby. Shehata carries on with her plot that targets Monsef, El-Doksh, and Magda. Mahmoud learns that Dalal's baby is safe and sound. Arnous has an exorcism to drive the Jinn out of his body.
Bossi and Ossa film Karim in a compromising position to make sure he doesn't betray them. Hend is reluctant about whether she should give Mohsen the formula. Marmar is shocked to learn that the exorcist she has resorted to is actually her sister Em Em. Monsef learns that Mahmoud is kidnapped.
Seeking atonement, Arnous intends to report his wife and Marmar to the police. Ossa asks Mohsen to convince Hend of following the commandment. Mahmoud survives a murder attempt plotted by El-Doksh and he starts working with Hamedto.
Bossi kidnaps Esaad to force Sabry to follow the commandment, but his indifference to her kidnapping comes as a surprise. Monsef learns of Mahmoud's plot. Marmar and Em Em head to the family house to read the commandments concerning them, but to everyone's shock, they go missing.
Sabry fulfills his commandment and three of his wives are murdered; only Esaad survives. Bossi tries to find the commandments and suspects that Hassan stole them. Shehata cooperates with Dalal to thwart Magda's plot. Arnous learns he is not possessed; he just has epilepsy.
Believing Hassan to have stolen the commandments, Bossi turns the people of the neighborhood against him, but Sabry states otherwise. Ossa tries to save the day, but Hassan is beaten to death, and it is eventually discovered that the commandments weren't stolen.
Bossi and Ossa find the commandments at the shrine and Marmar and Em Em get theirs. Marmar tells Nabil that she escaped from the police. Mohsen and Abu Ashraf (Ashraf's father) carry on with their plot to force Hend to do what they demand.
Bossi, Ossa, and Karim try to force Hend, Em Em, and Marmar to do what's in the commandments in order to fulfill the prophecy.
Marmar fulfills her commandment, and gives her money away. Likewise, Hend fulfills hers and confesses to coming up with a dangerous formula. Mahmoud learns of what happened with Magda and Monsef.
After much struggle, Em Em does what is in her commandment and Arnous dies. Bossi finds Monsef and Mahmoud and gives them their commandments.
Now that she has reunited her siblings, Bossi implements the final wish and poisons them, only to find out that Sabry deceived them and hasn't killed his wives. Karim and Ossa put the money in Ossa's bank account.
Kinda Alloush reads the scenario that Ossa sent her where she reveals the plan she devised to disinherit Sayed Nefisa's children, and how she replaced the checks he left them with fake commandments. Trying to atone for what she has done, Ossa looks after Bossi's children.