In 1985, Vincent tries to reconnect with his ex-wife, Andrea, when his relationship with Abby grows cold. Harvey and Candy are at odds trying to figure a way to keep pace in the future that is rapidly changing. Lori is sent back to work as she leaves rehab.
Frankie must confront Rudy as he seeks to boost his amateur porn business. As Lori defends herself on set, she is advised to be more amenable.
Abby becomes friends with Pilar, a graffiti artist, and the two embark on a trip. Candy asserts her opinion when she and Hank discuss money. Todd is forced to reevaluate his priorities, while Melissa must reckon with her past.
With Lori in the city for a couple of auditions, she crosses paths with familiar faces from the past. Candy tries to make herself heard at the Women Against Pornography meeting. Meanwhile, Alston must take a daring step.
Vincent goes down a perilous path when the club goes through difficult times. Paul tries to contact Todd's parents. Meanwhile, Candy and Harvey quarrel over a recent script, and Lori makes an appearance at a strip club.
A personal loss inspires Candy. Abby makes a shocking discovery and confronts Vincent about it. With AIDS becoming rampant in the NY gay community, Paul adopts an activist approach to help out.
Lori seeks Candy's help before going back to The Deuce. Meanwhile, Candy is busy trying to secure the funding for her film. Tommy tries to help Vincent make sense of the world they live in, with its challenges and intricacies.
Gene seems to see an ideal opportunity in the city's health crisis. Vincent wants to make peace with Abby. Candy must make an important decision regarding her and Hank's relationship.