In the aftermath of their car accident, Will rushes Natalie to the ED, where Phillip makes a startling announcement. The investigation into Cornelius Rhodes's death leads to tragic consequences that drive Connor away.
A power outage forces the doctors to prove their mettle in a constant battle to help their patients through. Natalie's first day back ends with her in a precarious position.
Crockett gets on April's bad side after a clash over a suspicious case. Ethan grapples with the unusual request of a terminal cancer patient.
As the doctors brace themselves to deal with the waves of outbreak victims, one of their own unknowingly gets too close to the culprit behind the release of the flesh-eating bacteria.
Natalie's actions with a patient bring her under fire. Crockett and Dr. Charles disagree on the best course of action to treat a patient's chronic pain. Maggie considers confiding in her friends about her diagnosis.
Natalie is forced to deal with the rising tension with both Phillip and Will. Noah gets in too deep with a patient he sympathizes with.
Ethan is forced to reckon with the unsavory reality of military enlistment and the medical care available to vets. Maggie finds romance in an unusual place.
Maggie takes drastic measures in the name of helping a friend. The staff struggles to deal when one of their own who falls victim to a violent assault.
Natalie finds out more information about who Phillip is. April receives shockings news that leaves her concerned about her future with Ethan.
As Dr. Charles deals with his wife's passing, April struggles to deal with the ramifications of her actions. Will is forced to confront an old medical decision when one of his patients ends up in the hospital.
Noah and April handle a preplexing case. The staff grows concerned for the life of one of their own in the wake of a plane crash.
Dr. Charles worries for Will when he learns of the latter's involvement with the safe injection site. Crockett takes a serious gamble in his attempt to save the life of two school children.
Natalie's interest is piqued by the unusual reaction of one of her patient's mother. Ethan, April, and Dr. Charles walk a fine line as they attempt to help the parents of two unwell children.
Will faces a dilemma when his work at the safe injection site clashes with his ethics. Dr. Charles and Elsa get involved in a case that could involve a misdiagnosis.
Will continues to grapple with doubt over Hannah's ability to work. Natalie and Dr. Charles must convince a dedicated actor to break character in order to save his life.
The lives of two doctors hang in the balance after a kidnapping. Will confronts the ramifications of his decision to turn Hannah in.
As wedding bells ring for Maggie, April's kiss with Crockett continues to haunt her. Natalie and Dr. Charles try to get to the bottom of a case that might involve child abuse.
Sharon and Dr. Charles question Will's judgment in a case involving a patient with Alzheimer's. Maggie and Ben try to support one of the latter's students when he is admitted to the hospital.
With Ethan and Crockett in open conflict, their connected patients force them into a tentative truce. Will tries to support Hannah in the wake of a difficult case.
With Crockett accused of murder, Natalie struggles to discern the truth and save him. Ethan takes a huge risk in an attempt to save a child's life.