As Grace returns from her travels feeling great, her joy is short-lived due to shocking news. Meanwhile, Karen gives Will tips on phone sex. Jack tries to get rid of Estefan's cuckoo clock.
Grace is unsure who is the father of her baby. Will asks Jack to help him prepare for having a straight son.
Will is having an issue with Jack regarding his hairline. Grace wants to prove to Mrs. Timmer that she can handle being a single mother. Karen takes on Stan's brother in a poker game.
Will and Grace get into an argument over whose task is more difficult regarding having a baby. Karen is trying to find someone to help her with her new baseball team.
In an attempt to help Will get over his break up with McCoy, Grace and Jack hire the Grief Panda to cheer him up. Grace is thinking of firing Karen.
Will meets a potential surrogate as he wants to become a father. Grace uses a trick to get into the AnnieCon.
Grace encounters an embarrassing situation with her neighbor. Will decides not to give Jack any more money to make him learn to be independent.
Will and Grace are trying to prove that their child is eligible of entering an elite school. Jack is causing trouble between Karen and her lover.
After finding out that her niece is dating a bisexual man, Grace decides to do something about it. Karen is having a hard time as she's on board of an economy flight.
Marilyn finds a couple who want to adopt Grace's baby. Will is helping Karen deal with a PR crisis. Jack and Estefan are having a hard time getting rid of a mouse.
Grace is trying to make things work out with her neighbor James, but she ends up causing him trouble at his work place. Jack takes Will to church.
Estefan wants Jack to buy Miss Coco Peru's bar. Karen makes Will and Grace meet her new lover.
Will and Grace think that Karen is in danger, as they rush to save her when she goes with her boyfriend to a cabin in the woods. Jack meets a reporter and tells him a fake story about his new bar.
As Karen tries to get back her ring, she finds out that Stan's new girlfriend is wearing it. Will and Grace are behaving like old folks when they're hosting Will's surrogate.
Will tries to spy on his surrogate by forcing Dr. DiLorenzo to go on a date with her. Karen wants to help Jack with a Broadway audition but she also needs to attend her team's championship celebration.
Because of Will's opinion about the Lucy show, Grace, Karen, and Jack imagine themselves to be Lucy while Will is Ricky.
Will and Grace go to look for a house, which makes them discuss their upcoming living arrangement. Jack needs to make a decision about pursing his dreams.
Will decides to forget the past and look ahead. Grace hasn't given birth yet. Karen wants to find closure with her ex-husband. Jack's dream of being on a Broadway stage becomes a reality.