When a pair of employees at a medical supply warehouse release a deadly gas into the air by accident, the fumes cause the dead to rise and go on a rampage into Louisville, Kentucky, in search of their favorite food, brains.
After finding a dead body in one of the drums, some kids let out the 2-4-5 Trioxen gas, which brings the dead back to life and makes them look for brains.
When his girlfriend Julie is killed in a motorcycle accident, the grief-stricken Curt decides to use his father's government project to bring the dead back to life on Julie. But as Julie turns into a living zombie, she struggles to deal with her violent new nature.
A gang of teens unintentionally releases a herd of brain-eating zombies while attempting to save a friend from the evil Hybra-Tech facility, where scientist Charles conducts experiments on zombies using toxic waste.
An unexpected resurrection of the living dead occurs when a college student accidentally creates and distributes a drug named "Z" on campus, causing chaos at a Halloween party.