Following the outbreak of Coronavirus, the staff at New Amsterdam struggles to deal with the situation, trying to save everyone they can. Meanwhile, a plane crash occurs in the city, and Iggy tries to help the pilot reveal the truth as investigators question the plane's crew.
Max must deal with the harrowing ramifications of one of his strategies. Meanwhile, Reynolds makes a comeback, and Bloom finds out something staggering regarding Iggy.
Max tries to fight a new proposal that promises more profits for New Amsterdam. Reynolds tries to handle a personal problem. As the unduly protective parents of a young girl won't let her leave the house during the pandemic, Iggy comes to her aid.
Bloom strives to provide a safe environment for her staff. Max goes to Connecticut to fetch Luna. Frome tries to help a woman in distress.
Max tries to help as Helen brings to his attention the fact that the blood supply at New Amsterdam is depleting fast. Reynolds comes to the realization that Bloom can teach him something useful.
While trying to end bigotry in New Amsterdam once and for all, Max gives the job of the new Medical Director to Helen, who already has a lot on her plate. Following an accident, the staff attends to the wounded.
Max provides free care to HIV-positive patients in New Amsterdam on National HIV Testing Day. Owing to their clashing bedside manners, Bloom and Reynolds have a squabble. Helen struggles to deal with her niece.
Max finds himself compelled to deal with the biases against non-white women in child labor, while Bloom has to handle the problem of crowdedness in the ED. Helen assists Dr. Agnes Kao with a distressing diagnosis.
Max sets out to provide free broadband access. Helen has to deliver some unpleasant news to an old patient. Reynolds attends to a girl who was shot.
Max has to deal with the past of New Amsterdam. Helen realizes that her teen niece needs a firm hand. Bloom and Reynolds attend to a patient who's in an unorthodox relationship.
Max brings about some radical reforms in hospital sustainability practices. Bloom comes back from vacation with a brand new frame of mind. Iggy comes upon a serious problem that involves an old patient.
A mess occurs in the ED following the bursting of a pipe. Max receives some unsettling news from Gwen and Calvin. Distressed about their kid, two parents are given advice by Iggy.
Max has to make a difficult decision regarding Luna. Helen tries to lend a helping hand to Mina. Bloom and Casey tend to a patient who's been harboring some secret for so long. Iggy lands in deep water.
As Max loses his wedding ring, he looks all over the hospital for it. Reynolds gets an unexpected offer. Iggy considers making a momentous change to his life. Bloom finds out some revelatory news regarding Leyla.