Louis meets the vampire Lestat in New Orleans in 1910, and his life begins to transform into unimaginable way.
Louis begins life as a vampire, then learns the rules of vampirism from his creator, Lestat, and discovers increasing differences between them. Louis also reveals more about his lifestyle as a modern-day vampire to Molloy.
Louis struggles to keep some semblance of humanity as he grapples to determine a vampire's true identity and the cravings that come with it, but things soon become worse.
Louis and Lestat's lives change completely after Claudia is transformed into a teenage vampire. They are forced to face questions about turning a teenager into a vampire, while Claudia discovers dark truths about her new life.
Claudia's behaviours and curiosities pose constant challenges to Louis and Lestat, but her actions spark an eruption that leads to an unexpected end.
Louis and Claudia resume their attempts to make Lestat part of the family, but after Lestat intervenes several times, their tolerance reaches the limit.
Claudia secretly plots to kill Lestat that even Louis is not aware of the details, while Louis divulges a new element in the interview that turns everything upside down.