After a failed love story, Dr. Ruby Walker arrives in a tropical South Indian town looking for a new job. All that follows is contrary to what she had in mind. She expected beaches, sunshine and palm trees but clashed heavily with the reality of work.
Doctor Ruby continues her work at an under-resourced hospital, where a heat wave brings dozens of heat-stroke sufferers to the hospital. She also takes on her first solo night shift before being put in danger due to a power outage.
After an absence of four months, Doctor Ruby returns to the hospital, leaving behind her family's clinic in the Indian tea plantation, but she soon discovers that her return will not be easy.
Doctor Ruby is forced to go to a remote village after the deadly Nipah virus spreads there, before facing difficult challenges when her actions have disastrous consequences. On the other hand, several conflicts take place inside Holby Hospital, and Lydia's secret is revealed to Doctor Greg.