In a world where mutants face systemic discrimination, a suburban family is forced to flee after their two children manifest mutant abilities.
With the teleportation taking its toll on Clarice, Caitlin and Eclipse race against the clock to try and help before she inadvertently attracts the attention of the police. Reed makes a questionable deal with Turner.
As Caitlin tries to figure out a way to help, a confrontation with her brother's neighbors threatens to turn ugly. Clarice gets training to better control her powers.
As a rescue mission is arranged to get to Polaris and Reed, Thunderbird unexpectedly reunites with an old friend that he thought dead.
Tension rises in the underground with Reed's arrival, leading him to take drastic measures to prove his loyalty. As Dreamer tries to get information from Turner about their program, Clarice comes to realize what Dreamer's powers did to her.
As the underground tries to get information on how the government has turned mutants against their own kind, Reed tries to mend his bridges with Andy as the latter's newfound powers worry him.
Polaris and Dreamer learn the truth about Eclipse's cooperation with Guerra. Thunderbird tries to convince Clarice to return with him to the underground. The underground learns that Reed's father is connected to the mutant program.
As the underground manages to rescue one of the Hounds, Reed's father reveals a shocking truth about his family origins and his work for Trask industries.
As Reed comes to realize the extent of his children's powers, a planned assault on a Trask power plant goes south, leaving Andy and Lauren with no choice but to join forces, though that poses a risk to everyone around them.
With the underground divided over how to proceed to rescue the captured mutants, Campbell tests Andy and Lauren's powers. An unexpected betrayal turns the tides as the mutants launch a raid on the SS.
As the Frost sisters try to manipulate various members of the underground to serve their own agenda, an attack from Turner and Campbell forces the underground into an uneasy alliance with the Hellfire Club.
As Esma reveals the history of the Hellfire Club, Campbell manages to get approval to expand the Hound program. Ellen gives the Struckers a lead to find out more about Otto's research.
With the underground besieged by Turner, the Struckers make a stand to allow the mutants to escape. Polaris makes a move against Campell and Montez on the behest of the Frost sisters.