After her husband divorces her, Esmat turns to her friend Gamila and they buy a villa. Karima disagrees with her son about managing the company and decides to leave her palace and live in a villa. Esmat and Karima discover that they were both swindled, and the villa was sold to both of them.
A strange man comes to the villa and claims to be the real owner, and assaults Esmat and Karima. It turns out that all this was with prior agreement between him and Karima, then another man comes claiming the same thing.
The pranks between Esmat and Karima continue, as each one attempts to take over the villa. Fawzia, Esmat's mother, decides to leave the nursing home where she lives, and Esmat invites her to live with her in the villa.
Esmat is reunited with her mother, Fawzia, at the villa, and she decides to throw her daughter's, Ola, engagement party there, but Karima is standing in her way. Esmat's son, Alaa, is attracted to Karima's business manager, Mai
Esmat's ex-husband, Kamal, attends their daughter's engagement party, and she reproaches him for divorcing her after all she has done for him. A dilemma occurs at the engagement party, but Karima saves the day.
Fawzia proposes to Esmat to open a home-food restaurant, but Karima steals their idea after Fawzia announces the idea, and she opens the restaurant in the garden of the villa.
After the success of Karima's restaurant project, she decides to seize the entire villa for the restaurant, and Esmat tries to spoil her plan, but Karima tries to persuade her to cooperate with her, and her mother Fawzia succeeds in convincing her.
Esmat and Karima try to help Gamila to overcome her sorrows, so they agree with Iyad to try to get close to her and impress her, which he successfully does.
Karima's nephew, Wa'el, comes to live with her in the villa for a while, but he causes discomfort for everyone as he gets close to Fawzia.
Once doctor Lou'ay comes to the villa to check on Fawzia, Esmat, Karima, and Gamila fall for him, striking a rivalry between them.
Kamal separates from his second wife and returns to speak with his ex-wife Esmat again. He talks to her about the piece of land that they bought before the divorce. When Kamal's second wife kicks him out, Esmat accepts for him to stay at the villa with her.
Esmat's younger sister, Sonia, arrives at the villa, and Esmat is resentful that the rug is pulled from under her after Sonia takes all of Fawzia's attention. Sonia asks her mother to come and live with her in Alexandria, but the mother prefers to stay with Esmat.
As Sayed comes to the villa, he tells his sister Karima that he wants to sing in cabarets, no matter how small he would get paid, but his sister is totally against it.
When Fawzia quarrels with Esmat, she decides to return to the nursing home again. As Esmat finds her at the nursing home, she tries to reconcile with her.
Karima's daughter suffers from a financial crisis when her money is stolen, and Karima decides to help her out by selling her share in the villa. However, when the police arrest the person who robbed the money from Karima's daughter, Karima changes her mind regarding the sale.
Everyone is worried about Fawzia because of the signs of fatigue and exhaustion that have their onset on her. Karima receives a visit from her younger sister, Shadia. Similarly, Layla, Esmat's cousin, visits her.
Karima's sister, Shadia, needs a kidney donor for the surgery, and everyone decides to get the money necessary for her operation, as well as money for Layla's surgery to restore her vision. It's revealed that Fawzia is perfectly fine and does not suffer anything.
University professor Mohab shows his admiration for Esmat, but she is afraid of getting into a relationship with him because of her current situation with her children. He reveals to her that he is still living with his ex-wife for his children's sake.
The two criminals, Al-Antably and Batata, decide to rob the villa, and they tie up Esmat, Karima, and Fawzia in order to steal their money.
It turns out that Al-Antably and Batata are stealing so that they have enough money to perform a kidney operation for Batata. Al-Antably helps Esmat after he accidentally injures her leg.
The security officer Amasha comes to the villa of Esmat and Karima, and Al-Antably and Batata know that there is a reward of half a million pounds for anyone who catches them. Hoping to get the money, they confess that they're the thieves, but Amasha doesn't believe them.
Escaping from Upper Egypt to evade a blood feud, Okasha arrives at the villa. When he tells the women that his mother lives in the villa, they do not believe him.
After Okasha leaves the villa, a man comes to tell the four women that Okasha's father has passed away and he inherited from him 100 million pounds. The women try to search for Okashs and be nice to him.
Karima encourages her daughter Tamara to ingratiate herself to Okasha, much to Esmat's distress. Okasha loses all his money, but Tamara still wants to be with him.
As Mother's Day approaches, Fawzia, Esmat, and Karima complain that their kids have neglected them, and Okasha decides to take the three of them on a vacation in Lebanon.
An auction takes place to sell half of Esmat and Karima's villa, and Okasha decides to buy it. Okasha hires a new business manager called Yulia, and Esmat feels that she's using him.
The four women try to warn Okasha that Yulia is trying to swindle him, but he does not listen to them. Okasha proposes to Yulia, and on the wedding day, the women's warnings prove correct when she runs away with all his properties.
A lawyer from Lebanon comes to inform both Esmat and Fawzia that they have become the legal heirs of Mrs. Georgina's palace, which is worth 50 million pounds. He gets a lot of money from them, but they discover that he's a fraud.
The four women decide to enlist the help of a Lebanese man named Gamal to find the conman who stole their money, and they succeed in getting their money back.
Fawzia tries to convince the women not to sell their shares in the villa so that they continue to enjoy the company of each other. After much thinking, they eventually decide not to give up the villa and to stay together.